Publications

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2017

"Bulk double emulsification for flow cytometric analysis of microfluidic droplets."
   D.J. Sukovich, S.C. Kim, N. Ahmed and A.R. Abate
   Analyst, DOI:10.1039/c7an01695f

"RNA-aptamers-in-droplets (RAPID) high throughput screening for secretory phenotypes."
   J. Abatemarco , M.F. Sarhan, J. M. Wagner , J-L. Lin , L. Liu, W. Hassouneh, S-F. Yuan , H.S. Alper and A.R. Abate
   Nature Communications, DOI: 10.1038/s41467-017-00425-7

"Cell-free extract based optimization of biomolecular circuits with droplet microfluidics."
   Y. Hori,  C. Kantak, R.M. Murray and A.R. Abate
   Lab on a Chip, DOI: 10.1039/c7lc00552k

"Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells."
   R.H. Cole, S. Tang , C. A. Siltanen , P. Shahi , J.Q. Zhang, S. Pousta , Z.J. Gartner and A.R. Abate
   PNAS, DOI: 10.1073/pnas.1704020114

"Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun."
   M. Karbaschi, P. Shahi, and A.R. Abate
   Biomicrofluidics, DOI: 10.1063/1.4995479

"Measurement of copy number variation in single cancer cells using rapid-emulsification digital droplet MDA"
   S. C. Kim, G. Premasekharan, I. C. Clark, H. B. Gemeda, P. L. Paris and A. R. Abate
   Microsystems & Nanoengineering, DOI: 10.1038/micronano.2017.18

"Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding"
   F. Lan, B. Demaree, N. Ahmed, and A.R. Abate
   Nature Biotechnology, DOI: 10.1038/nbt.3880

"Efficient extraction of oil from droplet microfluidic emulsions"
   J. R. Haliburton, S. C. Kim, I.C. Clark, R. A. Sperling, D. A. Weitz, and A. R. Abate
   Biomicrofluidics, DOI: 10.1063/1.4984035

"Finding a helix in a haystack: nucleic acid cytometry with droplet microfluidics"
   I. C. Clark and A. R. Abate
   Lab on a Chip, DOI: 10.1039/C7LC00241F, Critical Review

"Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding"
   P. Shahi, S. C. Kim, J. R. Haliburton, Z. J. Gartner & A. R. Abate
   Scientific Reports, DOI: 10.1038/srep44447

"Genetic interaction mapping with microfluidic-based single cell sequencing"
   J. R. Haliburton, W. Shao, A. Deutschbauer, A. Arkin, and A. R. Abate
   PloS One, DOI: 10.1371/journal.pone.0171302

"PCR-activated cell sorting as a general, cultivation-free method for high-throughput identification and enrichment of virus hosts"
   S. W. Lim, S. T. Lance, K. M. Stedman, Adam R. Abate
   Journal of Virological Methods, DOI: 10.1016/j.jviromet.2016.12.009


2016

"Sequence specific sorting of DNA molecules with FACS using 3dPCR"
   D. J. Sukovich, S. T. Lance, and A. R. Abate
   Scientific Reports, DOI: 10.1038/srep39385

"Peering below the diffraction limit: robust and specific sorting of viruses with flow cytometry"
   S. T. Lance, D. J. Sukovich, K. M. Stedman and A. R. Abate
   Virology Journal, DOI: 10.1186/s12985-016-0655-7

"Rapid Encapsulation of Cell and Polymer Solutions with Bubble-Triggered Droplet Generation"
   Z. Yan, I. C. Clark, A. R. Abate
   Macromolecular Chemistry and Physics, DOI: 10.1002/macp.201600297

"Operation of Droplet-Microfluidic Devices with a Lab Centrifuge"
   N. Ahmed, D. Sukovich and A. R. Abate
   Micromachines 2016, 7(9), 161; DOI: 10.3390/mi7090161

"Droplet barcoding for massively parallel single-molecule deep sequencing"
   F. Lan, J. R. Haliburton, A. Yuan, A. R. Abate
   Nature Communications 7, Article number: 11784 (2016) doi:10.1038/ncomms11784

"Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers."
   Cole, R. H., Gartner, Z. J., Abate, A. R.
   J. Vis. Exp., DOI: 10.3791/54010

"Electrical lysis of cells for detergent-free droplet assays"
   N. de Lange, T. M. Tran and A. R. Abate
   Biomicrofluidics, DOI: 10.1063/1.4944742


2015

"Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device"
   R. H. Cole, T. M. Tran, A. R. Abate
   Journal of Visualized Experiments, DOI: 10.3791/53516

"Enhanced sequencing coverage with digital droplet multiple displacement amplification"
   A. M. Sidore, F. Lan, S. W. Lim and . A. R. Abate
   Nucleic Acids Research DOI: 10.1093/nar/gkv1493

"Patterning microfluidic device wettability with spatially-controlled plasma oxidation"
   S. C. Kim, D. J. Sukovicha and A. R. Abate
   Lab Chip, DOI: 10.1039/C5LC00626K

"Compact and modular multicolour fluorescence detector for droplet microfluidics"
   R. H. Cole, N. Lange, Z. J. Gartner and A. R. Abate
   Lab Chip, DOI: 10.1039/c5lc00333d

"Dissecting enzyme function with microfluidic-based deep mutational scanning"
   P. A. Romero, T. M. Tran, and A. R. Abate
   Proc. Natl. Acad. Sci. U.S.A., DOI: 10.1073/pnas.1422285112 (2015)

"Microfluidic droplet enrichment for targeted sequencing"
   D. J. Eastburn, Y. Huang, M. Pellegrino, A. Sciambi, L. J. Ptáček and A. R. Abate
   Nucleic Acids Research DOI: 10.1093/nar/gkv297 (2015)

"PCR-Activated Cell Sorting for Cultivation-Free Enrichment and Sequencing of Rare Microbes"
   S. W. Lim,T. M. Tran,A. R. Abate
   PLoS ONE 10(1): e0113549 (2015)

"Rapid modulation of droplet composition with pincer microvalves"
  
C. J. Ochs, A. R. Abate
   Lab Chip, DOI: 10.1039/c4lc01040j (2015)

"Accurate sorting of microfluidic droplets at 30 kHz"
   A. Sciambi, A. R. Abate
   Lab Chip, DOI: 10.1039/c4lc01194e (2015)


2014

"Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia"
   E. Stieglitz, C. B. Troup, L. C. Gelston, J. Haliburton, E. D. Chow, K. B. Yu, J. Akutagawa, A. N. Taylor-Weiner, Y. L. Liu, Y.-D. Wang, K. Beckman, P. D. Emanuel, B. S. Braun, A. Abate, R. B. Gerbing, T. A. Alonzo, and M. L. Loh
   Blood, DOI: 10.1182/blood-2014-09-601690 (2014)

"Identification and genetic analysis of cancer cells with PCR-activated cell sorting"
   D. J. Eastburn, A. Sciambi, and A. R. Abate
   Nucleic Acids Research (2014)

"Picoinjection of Microfluidic Drops Without Metal Electrodes"
   B. O'Donovan, T.M. Tran, A. Sciambi, and A. R. Abate
   Journal of Visualized Experiments 86, e50913 (2014)

"Generating electric fields in PDMS microfluidic devices with salt water electrodes"
   A. Sciambi, A. R. Abate
   Lab Chip 14, 2605 (2014)

"Coaxial flow focusing in poly(dimethylsiloxane) microfluidic devices"
   T. M. Tran, S. Cater, and A. R. Abate
   Biomicrofluidics 8, 016502 (2014)


2013

"DNA sequence analysis with droplet-based microfluidics"
   A. R. Abate, T. Hung, R. A. Sperling, P. Mary, A. Rotem, J. J. Agresti, M. A. Weiner, and D. A. Weitz
   Lab Chip 13, 4864 (2013)

"Ultrahigh-throughput sorting of microfluidic drops with flow cytometry"
   S. W. Lim, A. R. Abate
   Lab Chip 13, 4563 (2013)

"Adding reagent to droplets with controlled rupture of encapsulated double emulsions"
   A. Sciambi, A. R. Abate
   Biomicrofluidics 7, 044112 (2013)

"Ultrahigh-throughput mammalian single-cell RT-PCR in microfluidic drops"
   D. J. Eastburn, A. Sciambi, A. R. Abate
   Analytical Chemistry 85, 8016-8021 (2013)

"Picoinjection Enables Digital Detection of RNA with Droplet RT-PCR"
   D. J. Eastburn, A. Sciambi, and A. R. Abate
   PLoS ONE 8, e62961 (2013)

"Block-and-break generation of microdroplets with fixed volume"
   V. Steijn, P. M. Korczyk, L. Derzsi, A. R. Abate, D. A. Weitz, and P. Garstecki
   Biomicrofluidics 7, 024108 (2013)

"From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology"
   T. M. Tran, F. Lan, C. S. Thompson and A. R. Abate
   Journal of Physics D: Applied Physics 46, 114004 (2013)

"Adhesive-based bonding technique for PDMS microfluidic devices"
   C. S. Thompson, A. R. Abate
   Lab Chip 13, 632 (2013)


2012

"Flow focusing geometry generates droplets through a plug and squeeze mechanism"
   P. A. Romero, A. R. Abate
   Lab Chip 12, 5130 (2012)

"Drop formation in non-planar microfluidic devices"
   A. Rotem, A. R. Abate, A. S. Utada, V. Van Steijn, D. A. Weitz
   Lab Chip 12, 4263 (2012)

"Electrode-free picoinjection of microfluidic drops"
   B. O'Donovan, D. J. Eastburn, A. R. Abate
   Lab Chip 12, 4029 (2012)

"Microfluidic synthesis of advanced microparticles for encapsulation and controlled release"
   W. J. Duncanson, T. Lin, A. R. Abate, S. Seiffert, R.K. Shaw, D. A. Weitz
   Lab Chip 12, 2135 (2012)

"Experimental validation of plugging during drop formation in a T-junction"
   A. R. Abate, P. Mary, V. van Steijn and D. A. Weitz
   Lab Chip 12, 1516 (2012)

"High throughput production of single core double emulsions in a parallelized microfluidic device"
   M. B. Romanowsky, A. R. Abate, A. Rotem, C. Holtze, and D. A. Weitz
   Lab Chip 12, 802 (2012)

"Non-coalescence of oppositely charged droplets in pH-sensitive emulsions"
   T. Liu, S. Seiffert, J. Thiele, A. R. Abate, D. A. Weitz, and W. Richtering
   Proc. Natl. Acad. Sci. U.S.A., 109, 384–389 (2011)

"Microfluidic techniques for synthesizing particles"

   A. R. Abate, S. Seiffert, A. S. Utada, A. Shum, R. Shah, J. Thiele, W. J. Duncanson, A. Abbaspourad, M. H. Lee, I. Akartuna, D. Lee, A. Rotem, D. A. Weitz
   Book Chapter Preprint

"Measuring the elastic modulus of microgels using microdrops"
   A.R. Abate, L. Han, L. Jin, Z. Suob, D.A. Weitz
   Soft Matter 8, 10032 (2012)


2011

"Efficient encapsulation with plug-triggered drop formation"
   A. R. Abate, A. Rotem, J. Thiele, and D. A. Weitz
   Phys. Rev. E 84, 031502 (2011)

"Controlling droplet incubation using close-packed plug flow"
   P. Mary, A. R. Abate, J. J. Agresti, and D. A. Weitz
   Biomicrofluidics 5, 024101 (2011)

"Observation of spatial propagation of amyloid assembly from single nuclei"
   T. P. J. Knowles, D. A. White, A. R. Abate, J. J. Agresti, S. I. A. Cohen, R. A. Sperling, E. J. De Genst,C. M. Dobson and D. A. Weitz
   Proc. Natl. Acad. Sci. U.S.A., 108, 14746-14751, (2011)

"Early development drug formulation on a chip: Fabrication of nanoparticles using a microfluidic spray dryer"
   J. Thiele, M. Windbergs, A. R. Abate, M. Trebbin, H. C. Shum, S. Förster and D. A. Weitz
   Lab Chip 11, 2362 (2011)

"On-chip background noise reduction for cell-based assays in droplets"
   P. Mary, A. Chen, I. Chen, A. R. Abate, and D. A. Weitz
   Lab Chip 11, 2066 (2011)

“Faster multiple emulsification with drop splitting”
   A. R. Abate and D. A. Weitz
   Lab Chip 11, 1911 (2011)

“Air-bubble-triggered drop formation in microfluidics”
   A. R. Abate and D. A. Weitz
   Lab Chip 11, 1713 (2011)

“Synthesis of monodisperse microparticles from non-newtonian polymer solutions with microfluidic devices”
   A. R. Abate, M. Kutsovsky, S. Seiffert, M. Windbergs, L. F. V. Pinto, A. Rotem, A. S. Utada and D. A. Weitz
   Advanced Materials 23, 1757–1760 (2011)

“Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions”
   A. R. Abate and D. A. Weitz
   Biomicrofluidics, 5, 014107 (2011)

“One-step formation of multiple emulsions in microfluidics”
   A. R. Abate, J. Thiele, and D. A. Weitz
   Lab Chip, 11, 253-258 (2011)


2010

“High-throughput injection with microfluidics using picoinjectors”
   A. R. Abate, T. Hung, P. Mary, J. J. Agresti, and D. A. Weitz
   Proc. Natl. Acad. Sci. U.S.A. 107, 19163-19166 (2010)

“Fabrication of polymersomes using double-emulsion templates in glass-coated stamped microfluidic devices”
   J. Thiele, A. R. Abate, H. C. Shum, S. Bachtler, S. Forster, and D. A. Weitz
   Small, 6, 1723-1727 (2010)

“Patterning microfluidic device wettability using flow confinement”
   A. R. Abate, J. Thiele, M. Weinhart, and D. A. Weitz
   Lab Chip, 10, 1774-1776 (2010)

“Functional patterning of PDMS microfluidic devices using integrated chemo-masks”
   M. B. Romanowsky, M. Heymann, A. R. Abate, A. T. Krummel, S. Fraden, and D. A. Weitz
   Lab Chip, 10, 1521-1524 (2010)

“Microfluidic sorting with high-speed single-layer membrane valves”
   A. R. Abate, J. J. Agresti, and D. A. Weitz
   Appl. Phys. Lett., 96, 203509, (2010)

“Smart microgel capsules from macromolecular precursors”
   S. Seiffert, J. Thiele, A. R. Abate, and D. A. Weitz
   J. Am. Chem. Soc., 132, 6606-6609 (2010)

“High-throughput fluorescence detection using an integrated zone-plate array”
   E. Schonbrun, A. R. Abate, P. Steinvurzel, D. A. Weitz, K. Crozier
   Lab Chip, 10, 852-856 (2010)

“Ultrahigh-throughput screening in drop-based microfluidics for directed evolution”
   J. J. Agresti, E. Antipov, A. R. Abate, K. Ahn, A. C. Rowat, J. C. Baret, M. Marquez, A. M. Klibanov, A. D. Griffiths, and D. A. Weitz
   Proc. Natl. Acad. Sci. U.S.A., 107, 6550 (2010)

“Jamming and growth of dynamical heterogeneities versus depth for granular heap flow”
   H. Katsuragi, A. R. Abate, and D. J. Durian
   Soft Matter, 6, 3023-3029 (2010)

“Droplet microfluidics for fabrication of non-spherical particles”
   H. C. Shum, A. R. Abate, a D. Lee, A. Studart, B. Wang, C. H. Chen, J. Thiele, A. T. Krummel and D. A. Weitz
   Macromol. Rapid Comm., 31, 108-118 (2010)


2009

"Functionalized Glass Coating for PDMS Microfluidic Devices"
   A. R. Abate, D. Lee, C. Holtze, A. Krummel, T. Do, and D. A. Weitz
   Lab on a Chip Technology (Vol 1): Fabrication and Microfluidics, 17 (2009)

“Impact of inlet channel geometry on microfluidic drop formation”
   A. R. Abate, A. Poitzsch, Y. Hwang, J. Lee, J. Czerwinska, and D. A. Weitz
   Phys. Rev. E, 80, 026310 (2009)

“High-order multiple emulsions formed in poly(dimethylsiloxane) microfluidics”
   A. R. Abate and D. A. Weitz
   Small, 5, 2030-2032 (2009)

“A multi-color fast-switching microfluidic droplet dye laser”
   S. K. Y. Tang, Z. Li, A. R. Abate, J. J. Agresti, D. A. Weitz, D. Psaltis, and G. M. Whitesides
   Lab Chip, 9, 19, 2767-2771 (2009)

“Beating Poisson encapsulation statistics using close-packed ordering”
   A. R. Abate, C. H. Chen, J. J. Agresti, and D. A. Weitz
   Lab Chip, 9, 2628-2631 (2009)

“Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices”
   T. Franke, A. R. Abate, D. A. Weitz, and A. Wixforth
   Lab Chip,  9, 2625-2627 (2009)

“Microfluidic assembly of magnetic hydrogel particles with uniformly anisotropic structure”
   C. H. Chen, A. R. Abate, D. Lee, E. M. Terentjev, and D. A. Weitz,
   Adv. Mater, 21, 3201-3204 (2009).

“Valve-based flow focusing for drop formation”
   A. R. Abate, M. B. Romanowsky, J. J. Agresti, and D. A. Weitz
   Appl. Phys. Lett. 94, 023503 (2009)

“Janus particles templated from double emulsion droplets generated using microfluidics”
   C. H. Chen, R. K. Shah, A. R. Abate, and D. A. Weitz
   Langmuir 25, 4320-4323 (2009)


2008

“Single-layer membrane valves for elastomeric microfluidic devices”
   A. R. Abate and D. A. Weitz
   Appl. Phys. Lett. 92, 243509 (2008)

“Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability”
   A. R. Abate, A. T. Krummel, D. Lee, C. Holtze, and D. A. Weitz
   Lab Chip 8, 2157-2160 (2008)

Effective temperatures and activated dynamics for a two-dimensional air-driven granular system on two approaches to jamming
   A. R. Abate and D. J. Durian
   Phys. Rev. Lett. 101, 245701 (2008)

Glass coating for PDMS microfluidic channels by sol-gel methods
   A. R. Abate, D. Lee, T. Do, C. Holtze, and D. A. Weitz
   Lab Chip 8, 516-518 (2008)


2007

Topological persistence and dynamical heterogeneities near jamming
   A. R. Abate and D. J. Durian
   Phys. Rev. E 76, 021306 (2007)

Measurement of growing dynamical length scales and prediction of the jamming transition in a granular material
   A. S. Keys, A. R. Abate, S. C. Glotzer, and D. J. Durian
   Nat. Phys. 3, 260-264 (2007) * Co-first Authors

Spatially heterogeneous dynamics in a granular system near jamming
   A. R. Abate and D. J. Durian
   Chaos 17, 041107 (2007)

Avalanche statistics and time-resolved grain dynamics for a driven heap
   A. R. Abate, H. Katsuragi, and D. J. Durian
   Phys. Rev. E 76, 061301 (2007)


2006

Approach to jamming in an air-fluidized granular bed
   A. R. Abate and D. J. Durian
   Phys. Rev. E 74, 031308 (2006)


2005

Partition of energy for air-fluidized grains
   A. R. Abate and D. J. Durian
   Phys. Rev. E 72, 031305 (2005)

Statistical characterization of the forces on spheres in an upflow of air
   R. P. Ojha, A. R. Abate, and D. J. Durian
   Phys. Rev. E 71, 016313 (2005)


2004

Penetration depth for shallow impact cratering
   M. A. Ambroso, C. R. Santore, A. R. Abate, and D. J. Durian
   Phys. Rev. E 1, 0411231 (2004)


2002

Superconductivity, incoherence and Anderson localization in the crystalline organic conductor (BEDT-TTF)3Cl2• 2H2O at high pressures
   P. Goddard, S. W. Tozer, J. Singleton, A. Ardavan, A. Abate, and M. Kurmoo
   J. Phys. Condens. Matter 14, 7345-7361 (2002)

Adhesives for highly polished surfaces and low temperature: A simple test and results
   I. F. Silvera, A. Abate, A. Chijioke, and A. Pashin
   Rev. Sci. Instrum. 73, 2108-2114 (2002)